A Review Of pentobarbital sodium use
A Review Of pentobarbital sodium use
Blog Article
pentobarbital will lower the level or effect of buprenorphine, prolonged-performing injection by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Closely. Clients who transfer to buprenorphine long-performing injection from transmucosal buprenorphine coadministered with CYP3A4 inducers ought to be monitored to be certain buprenorphine plasma amounts are enough.
pentobarbital will lower the level or effect of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Animal info. Phenobarbital sodium is carcinogenic in mice and rats just after lifetime administration. In mice, it developed benign and malignant liver mobile tumors. In rats, benign liver mobile tumors were observed really late in life.
pentobarbital will lessen the level or effect of prednisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Contraindicated (1)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can reduce panobinostat amounts by ~70% and bring on procedure failure.
pentobarbital will lower the extent or effect of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives could be decreased. Usage of a nonhormonal contraceptive is usually recommended.
pentobarbital will minimize the level or effect of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the level or effect of estradiol vaginal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will minimize the extent or effect of nitrendipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
pentobarbital will decrease the level or effect of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or effect of etravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lessen the level or effect of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
pentobarbital will reduce the extent or effect get more info of conivaptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (name Formerly used: bishydroxycoumarin) and causes a minimize in anticoagulant action as calculated through the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing improved metabolism and decreased anticoagulant response of oral anticoagulants (e.